Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 13/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943401 | 0.80 | PDE10A (0.56) | PDE10AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27981595 | 0.80 | PDE10A (0.56) | PDE10AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1031078 | 0.76 | PDE10A (0.59) | PDE10AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27964913 | 0.75 | ALDH1A1 (0.54) | PIN1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28282006 | 0.75 | PDE10A (0.62) | PDE10AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11326420 | 0.74 | PDE10A (0.61) | PDE10AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL34471419 | 0.73 | MEN1 (0.53) | PDE10AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4167767 | 0.73 | ALDH1A1 (0.54) | PDE10APIN1MEN1KMT2AALDH1A1 | |
| SCHEMBL27798082 | 0.73 | GSK3B (0.64) | PDE10APIN1MEN1KMT2AALDH1A1 | |
| SCHEMBL2917596 | 0.72 | NOS1 (0.39) | PDE10AMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492028-A | Novel sulfonaminoquinoline hepcidin antagonists | VIFOR INT AG | 2014-01-01 | — | — | CN | disclosed |
| CN-103102315-A | Quinazoline arylurea and preparation method and application thereof | UNIV YUNNAN | 2013-05-15 | — | — | CN | disclosed |
| CN-1044245-C | Tricyclic Dicarbonyl derivatives | HAFFMANN LA ROCHE AG F (DE) | 1999-07-21 | — | — | CN | disclosed |
| CN-1149295-A | Tricyclic Dicarbonyl derivatives | HOFFMANN LA ROCHE (CH) | 1997-05-07 | — | — | CN | disclosed |