SCHEMBL27965002

SCHEMBL27965002

O=S(=O)(O)c1ccc2c(c1S(=O)(=O)O)Cc1ccccc1O2

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.47
MAOB P27338 3/20 0.47
ACSL1 P33121 1/20 0.37
MAPKAPK2 P49137 1/20 0.36
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30422927 1.00 MAOA (0.47) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL10896712 0.87 MAOA (0.46) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL10896702 0.85 MAOA (0.44) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL2098386 0.84 MAOA (0.50) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL28310829 0.83 MAOA (0.42) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL27483660 0.78 MAOA (0.35) MAOAMAOBACSL1
Xanthene SCHEMBL5165289 0.76 MAOA (0.74) MAOAMAOBACSL1MAPKAPK2NPC1
Xanthene SCHEMBL27836662 0.73 MAOA (0.68) MAOAMAOBACSL1MAPKAPK2NPC1
Xanthene SCHEMBL27836663 0.73 MAOA (0.68) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL3165971 0.73 NPC1 (0.42) MAOANPC1LMNARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103765258-A Three-dimensional circular polarization eyeglasses CRYSOPTIX KK 2014-04-30 CN claimed
CN-103765258-A Three-dimensional circular polarization eyeglasses CRYSOPTIX KK 2014-04-30 CN disclosed