SCHEMBL10896702

SCHEMBL10896702

O=S(=O)(O)c1ccc2c(c1Cl)Cc1ccccc1O2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.44
MAOB P27338 2/20 0.44
ACSL1 P33121 1/20 0.36
MAPKAPK2 P49137 1/20 0.35
PTGER1 P34995 3/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32
PMP22 Q01453 1/20 0.32
KMT2A Q03164 1/20 0.32
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30422927 0.85 MAOA (0.47) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL27965002 0.85 MAOA (0.47) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL2098386 0.82 MAOA (0.50) MAOAMAOBACSL1MAPKAPK2CYP1A2
SCHEMBL10896712 0.81 MAOA (0.46) MAOAMAOBACSL1MAPKAPK2PTGER1
SCHEMBL28310829 0.81 MAOA (0.42) MAOAMAOBACSL1MAPKAPK2MEN1
SCHEMBL9124376 0.77 MAOA (0.55) MAOAMAOBACSL1MAPKAPK2NPC1
SCHEMBL25392921 0.74 MAOA (0.52) MAOAMAOBACSL1MAPKAPK2MEN1
Xanthene SCHEMBL5165289 0.74 MAOA (0.74) MAOAMAOBACSL1MAPKAPK2MEN1
SCHEMBL17179942 0.73 MAOA (0.37) MAOAMAOBMAPKAPK2NPC1RAB9A
Xanthene SCHEMBL27836663 0.71 MAOA (0.68) MAOAMAOBACSL1MAPKAPK2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4598158-A CHROMAGEN HAVING A DIFFUSION CONTROL MOIETY;SELF-DEVELOP COLOR FILMS POLAROID CORPORATION, PATENT DEPT. (US) 1986-07-01 US disclosed
US-4420627-A Hydrazine dyes POLAROID CORPORATION (US) 1983-12-13 US disclosed
EP-0082506-A2 Photosensitive element, film unit, photographic process and dyes POLAROID CORPORATION (US) 1983-06-29 EP disclosed
US-4386150-A CHROMAGENS HAVING A DYE MOIETY, A NITROGEN-NITROGEN MOIETY, AND A DIFFUSION-CONJTROLLING HYDROQUINONYL MOIETY; COLOR FILMS POLAROID CORPORATION (US) 1983-05-31 US disclosed