Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244757 | 0.78 | TLR9 (0.43) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30769910 | 0.78 | TLR9 (0.43) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL27035336 | 0.76 | HTR2C (0.42) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL27035428 | 0.75 | HRH4 (0.41) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28131823 | 0.73 | HTR6 (0.38) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9206473 | 0.73 | CNR1 (0.36) | RET | |
| SCHEMBL19581178 | 0.73 | HTR2C (0.46) | HTR2C | |
| SCHEMBL16879006 | 0.73 | RET (0.36) | RET | |
| SCHEMBL8562692 | 0.72 | HTT (0.40) | HTR6HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16836549 | 0.72 | BTK (0.41) | PARP1IKBKBCHUKHTR6ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827089-A | Novel compound having angiogenesis inhibitory activity, method for preparing same, and pharmaceutical composition comprising same | BORYUNG PHARM | 2014-05-28 | — | — | CN | claimed |
| CN-103827089-A | Novel compound having angiogenesis inhibitory activity, method for preparing same, and pharmaceutical composition comprising same | BORYUNG PHARM | 2014-05-28 | — | — | CN | disclosed |