Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6111608 | 0.90 | SPR (0.57) | SPRNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL5244703 | 0.90 | SPR (0.57) | SPRNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL27965179 | 0.87 | LTA4H (0.56) | SPRNPC1RAB9AEPHX1EPHX2 | |
| SCHEMBL27965491 | 0.85 | SPR (0.47) | SPRNPC1RAB9AEPHX2 | |
| SCHEMBL21958177 | 0.84 | EGFR (0.54) | SPR | |
| SCHEMBL3801054 | 0.83 | SPR (0.50) | SPRNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL23360463 | 0.81 | SPR (0.50) | SPRSMN1; SMN2EPHX1CCR5 | |
| SCHEMBL23360461 | 0.81 | SPR (0.50) | SPRSMN1; SMN2EPHX1CCR5 | |
| SCHEMBL28188379 | 0.81 | GFER (0.51) | SPR | |
| SCHEMBL7465143 | 0.80 | KDM4E (0.51) | SPREPHX1EPHX2CCR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103983627-A | Pyridopyrimidine compounds as anti-tubercular agents | PASTEUR INSTITUT KOREA | 2014-08-13 | — | — | CN | disclosed |
| CN-102105470-B | Pyridopyrimidine compounds as antitubercular agents | PASTEUR INSTITUT KOREA | 2014-06-04 | — | — | CN | disclosed |