Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | TP53 | P04637 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31315035 | 0.86 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL31315034 | 0.86 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL16228089 | 0.82 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL29563561 | 0.79 | NPC1 (0.69) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL12075548 | 0.79 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL914225 | 0.79 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL31595811 | 0.79 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL14091615 | 0.79 | PDE5A (0.58) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL22901570 | 0.79 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL14091330 | 0.79 | METAP2 (0.46) | RAB9ANPC1SMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103772439-B | A kind of quinoline benzimidazole Group IVB list half metallocene and its preparation method and application and the method for olefinic polyreaction | 中国石油化工股份有限公司 | 2016-07-13 | — | — | CN | claimed |
| CN-103772439-B | A kind of quinoline benzimidazole Group IVB list half metallocene and its preparation method and application and the method for olefinic polyreaction | 中国石油化工股份有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-103772439-A | Quinoline-benzimidazole IVB group mono-Cp complex, preparation method and application thereof and method for polymerization reaction of olefin | CHINA PETROLEUM & CHEMICAL | 2014-05-07 | — | — | CN | disclosed |