Ethoxycarbonyl Group

Ethoxycarbonyl Group

SCHEMBL27965698

CCOC=O.c1cc(CCN2CCCC2)c[nH]1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 11/20 0.42
SLC6A3 Q01959 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
SIGMAR1 Q99720 2/20 0.40
MBTD1 Q05BQ5 1/20 0.40
L3MBTL3 Q96JM7 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
HTR1D P28221 1/20 0.37
HTR1B P28222 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL27825846 0.79 CAPN1 (0.42) CYP1A2
Ethoxycarbonyl Group SCHEMBL27908382 0.78 TRPM8 (0.36) CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL27825879 0.71 TRPM8 (0.33)
SCHEMBL27715604 0.71 CAPN1 (0.46)
Ethoxycarbonyl Group SCHEMBL27926110 0.70 TRPM8 (0.34) CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL27883122 0.68 TSHR (0.31) TDP1CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL27911630 0.68 CYP1A2 (0.30) CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL27983036 0.68 CYP1A2 (0.30) CYP1A2CYP3A4
Ethoxycarbonyl Group SCHEMBL27766540 0.67
SCHEMBL8021517 0.66 HRH3 (0.59) HRH3L3MBTL1MBTD1L3MBTL3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101987848-B New dihydroindolone derivatives, method of preparing same and pharmaceutical compositions containing the same SERVIER LAB 2014-06-18 CN disclosed