SCHEMBL27965733

SCHEMBL27965733

COC(=O)C(c1ccc(O)cc1)c1ccccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
KMT2A Q03164 2/20 0.41
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP13 P45452 1/20 0.40
CASP1 P29466 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
THRB P10828 1/20 0.39
NR1I2 O75469 1/20 0.39
ABCB11 O95342 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
CYP2B6 P20813 1/20 0.39
DRD1 P21728 1/20 0.39
HTR2A P28223 1/20 0.39
SLC6A4 P31645 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4384096 0.87 KMT2A (0.40) KMT2ACASP1ALDH1A1THRBNR1I2
SCHEMBL13749034 0.84 ESR1 (0.46) ESR1ESR2KMT2AMMP2MMP9
SCHEMBL2843638 0.80 KMT2A (0.58) ESR1ESR2KMT2AMMP2MMP9
SCHEMBL384968 0.80 ESR1 (0.58) ESR1ESR2KMT2AMMP2MMP9
SCHEMBL27965728 0.79 ALDH1A1 (0.43) ESR1ESR2KMT2AALDH1A1GAA
SCHEMBL27965750 0.79 L3MBTL1 (0.50) ESR1ESR2MMP2MMP9MMP13
Methane SCHEMBL28696266 0.79 KMT2A (0.56) ESR1ESR2KMT2AMMP2MMP9
SCHEMBL28575879 0.76 ATM (0.51) KMT2AALDH1A1CYP2C19CNR1CYP2D6
SCHEMBL6487230 0.75 ALDH1A1 (0.56) KMT2ACASP1ALDH1A1THRBNR1I2
SCHEMBL27469447 0.74 KMT2A (0.55) KMT2AALDH1A1GAACHRM2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103936537-B A kind of phenol of golden catalysis and the selectivity c h bond functionalization method of aniline EAST CHINA NORMAL UNIVERSITY (CN) 2015-10-28 CN disclosed
CN-103936537-A Method for performing gold-catalyzed selective C-H bond functionalization on phenol and aniline UNIV EAST CHINA NORMAL 2014-07-23 CN disclosed