SCHEMBL27965752

SCHEMBL27965752

CC(C(=O)O)(c1ccccc1)c1cccc(O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
HSD17B1 P14061 1/20 0.47
HSD17B2 P37059 1/20 0.47
KIF11 P52732 5/20 0.43
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
CYP3A4 P08684 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CA12 O43570 2/20 0.42
CA2 P00918 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26629506 0.96 HSD17B1 (0.49) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL73063 0.84 HDAC3 (0.61) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL9778285 0.82 ESR1 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
Hydrochloric Acid SCHEMBL3674757 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
Hydrogen Sulfide SCHEMBL27894390 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28079327 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28727492 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
Bromomethane SCHEMBL209562 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
Hydrogen Sulfide SCHEMBL28066375 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL28079189 0.82 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117813017-A Method for improving intestinal microbiota diversity 雀巢产品有限公司 2024-04-02 CN disclosed
CN-112040966-A Treating xerophthalmia 云南拜奥泰克生物技术有限责任公司 2020-12-04 CN disclosed
CN-111821370-A Compositions and methods for treating dry eye 云南拜奥泰克生物技术有限责任公司 2020-10-27 CN disclosed
CN-103936537-B A kind of phenol of golden catalysis and the selectivity c h bond functionalization method of aniline EAST CHINA NORMAL UNIVERSITY (CN) 2015-10-28 CN disclosed
CN-103936537-A Method for performing gold-catalyzed selective C-H bond functionalization on phenol and aniline UNIV EAST CHINA NORMAL 2014-07-23 CN disclosed