Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 3/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27662780 | 0.87 | AGXT (0.56) | AGXTPRMT6ADRA2CDRD2DRD3 | |
| SCHEMBL28322327 | 0.84 | AGXT (0.46) | AGXTPRMT6ADRA2CDRD2DRD3 | |
| SCHEMBL109344 | 0.82 | AGXT (0.69) | AGXTPRMT6ADRA2CMAPT | |
| SCHEMBL109316 | 0.80 | AGXT (0.67) | AGXTPRMT6MAPT | |
| SCHEMBL2376462 | 0.79 | CHRNA7 (0.59) | AGXTPRMT6DRD2DRD3DRD4 | |
| SCHEMBL27468903 | 0.79 | AGXT (0.49) | AGXTPRMT6ADRA2CDRD2DRD3 | |
| SCHEMBL5095800 | 0.78 | AGXT (0.65) | AGXTPRMT6MAPT | |
| SCHEMBL113799 | 0.78 | AGXT (0.65) | AGXTPRMT6MAPT | |
| SCHEMBL6263381 | 0.78 | DRD4 (0.70) | PRMT6DRD2DRD3SIGMAR1DRD4 | |
| SCHEMBL28322328 | 0.78 | AKR1C3 (0.54) | AGXTITGB3ITGA2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102458399-B | New pharmaceutical use of centhaquin | UNIV MIDWESTERN | 2014-04-23 | — | — | CN | claimed |