Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27662780 | 0.87 | AGXT (0.56) | AGXTSIGMAR1DRD2DRD3ITGB3 | |
| SCHEMBL10224842 | 0.84 | MGLL (0.47) | AGXTSIGMAR1DRD2DRD3PRMT6 | |
| SCHEMBL27966422 | 0.84 | AGXT (0.49) | AGXTSIGMAR1DRD2DRD3ITGB3 | |
| SCHEMBL28322328 | 0.81 | AKR1C3 (0.54) | AGXTITGB3ITGA2BGRM5ALDH1A1 | |
| Ethane SCHEMBL27848243 | 0.81 | PDGFRB (0.44) | ITGB3ITGA2BALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL109316 | 0.80 | AGXT (0.67) | AGXTPRMT6ALDH1A1MAPT | |
| SCHEMBL24677569 | 0.79 | MEN1 (0.51) | SIGMAR1GRM5ALDH1A1LMNAMAPT | |
| SCHEMBL27468903 | 0.79 | AGXT (0.49) | AGXTSIGMAR1DRD2DRD3ITGB3 | |
| SCHEMBL109344 | 0.79 | AGXT (0.69) | AGXTPRMT6ALDH1A1MAPTADRA2C | |
| SCHEMBL5095800 | 0.78 | AGXT (0.65) | AGXTPRMT6ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110337293-A | Therapeutic compound | 新泽西鲁特格斯州立大学 | 2019-10-15 | — | — | CN | claimed |