Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1632768 | 0.82 | POLB (0.44) | POLBL3MBTL1DPP4PREPFAP | |
| SCHEMBL8304001 | 0.80 | DPP4 (0.58) | POLBL3MBTL1DPP4PREPFAP | |
| SCHEMBL27937090 | 0.80 | EPHX2 (0.41) | POLBL3MBTL1DPP4PREPFAP | |
| SCHEMBL1631839 | 0.80 | DPP4 (0.58) | POLBL3MBTL1DPP4PREPFAP | |
| SCHEMBL17057232 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBL3MBTL1DPP4 | |
| SCHEMBL1631028 | 0.77 | DPP4 (0.42) | POLBL3MBTL1DPP4PREPFAP | |
| SCHEMBL14000163 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNAPOLBL3MBTL1DPP4 | |
| SCHEMBL11841155 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL13997163 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNAPOLBL3MBTL1 | |
| SCHEMBL8658446 | 0.76 | PREP (0.47) | POLBL3MBTL1DPP4PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103804266-A | Synthetic method of vildagliptin intermediate | ZHANGJIAGANG WEISHENG BIOLOG MEDICAL CO LTD | 2014-05-21 | — | — | CN | disclosed |