Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29906720 | 1.00 | EGFR (0.41) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL27974167 | 0.91 | EGFR (0.35) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL12610928 | 0.80 | EGFR (0.44) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL29391916 | 0.80 | EGFR (0.44) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL7094509 | 0.78 | HPGDS (0.40) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL12610896 | 0.77 | EGFR (0.42) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL4793575 | 0.77 | ALDH1A1 (0.45) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL4795864 | 0.74 | ALDH1A1 (0.45) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL7092502 | 0.74 | HPGDS (0.40) | EGFRALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL29906737 | 0.74 | CYP11B1 (0.45) | ALDH1A1MAPTKDM4EHPGDPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965213-A | 7,8-Dihydro-6H-[1,4]oxazine[3,2-g]quinazoline derivatives, and preparation method and use thereof | JIANGSU AOSAIKANG PHARM CO LTD | 2014-08-06 | — | — | CN | disclosed |
| CN-103965213-A | 7,8-Dihydro-6H-[1,4]oxazine[3,2-g]quinazoline derivatives, and preparation method and use thereof | JIANGSU AOSAIKANG PHARM CO LTD | 2014-08-06 | — | — | CN | disclosed |