Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | WRN | Q14191 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1680417 | 0.89 | CYP2A6 (0.53) | CALM1ALDH1A1HPGDLMNALTA4H | |
| SCHEMBL27968338 | 0.89 | TP53 (0.48) | CALM1ALDH1A1HPGDLMNALTA4H | |
| SCHEMBL5108763 | 0.89 | TSHR (0.48) | CALM1ALDH1A1HPGDLMNALTA4H | |
| (Z)-1,2-Diphenylethene SCHEMBL28198243 | 0.87 | CALM1 (0.44) | CALM1ALDH1A1HPGDLMNALTA4H | |
| SCHEMBL17800248 | 0.85 | HTR2A (0.52) | CALM1ALDH1A1HPGDALOX5SMN1; SMN2 | |
| SCHEMBL27968429 | 0.85 | LMNA (0.43) | CALM1ALDH1A1HPGDLMNALTA4H | |
| SCHEMBL11406994 | 0.84 | CALM1 (0.46) | CALM1ALDH1A1HPGDLMNALTA4H | |
| SCHEMBL146369 | 0.84 | TP53 (0.61) | CALM1ALDH1A1HPGDLMNALTA4H | |
| SCHEMBL10789831 | 0.84 | CALM1 (0.46) | CALM1ALDH1A1HPGDLMNALTA4H | |
| SCHEMBL3327471 | 0.84 | CALM1 (0.46) | CALM1ALDH1A1HPGDLMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214471-B | The preparation method of compound with Na-dependent glucose transporter inhibitory activity | 田边三菱制药株式会社 | 2018-02-06 | — | — | CN | disclosed |
| CN-104109155-A | Novel compounds | TANABE SEIYAKU CO | 2014-10-22 | — | — | CN | disclosed |
| CN-103819465-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2014-05-28 | — | — | CN | disclosed |