Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 9/20 | 0.55 |
| ▸ | DRD2 | P14416 | 7/20 | 0.55 |
| ▸ | DRD3 | P35462 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15945060 | 0.85 | DRD4 (0.55) | DRD4DRD2DRD3GAAMAPT | |
| SCHEMBL27527099 | 0.84 | LTA4H (0.57) | DRD4DRD2DRD3GAAMAPT | |
| SCHEMBL9608917 | 0.81 | DRD4 (0.55) | DRD4DRD2DRD3GAAMAPT | |
| SCHEMBL8276924 | 0.81 | DRD4 (0.55) | DRD4DRD2DRD3GAAMPO | |
| SCHEMBL27163243 | 0.81 | DRD4 (0.55) | DRD4DRD2DRD3GAAMPO | |
| SCHEMBL6852145 | 0.81 | DRD4 (0.55) | DRD4DRD2DRD3GAAMPO | |
| SCHEMBL2412911 | 0.81 | GAA (0.58) | DRD4DRD2DRD3GAAMAPT | |
| SCHEMBL2408942 | 0.81 | DRD4 (0.55) | DRD4DRD2DRD3GAAMAPT | |
| SCHEMBL4810042 | 0.80 | DRD4 (0.51) | DRD4DRD2DRD3GAAMPO | |
| SCHEMBL15945077 | 0.79 | DRD4 (0.54) | DRD4DRD2DRD3GAAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104109155-A | Novel compounds | TANABE SEIYAKU CO | 2014-10-22 | — | — | CN | disclosed |
| CN-103819465-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2014-05-28 | — | — | CN | disclosed |