Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27968624 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAKMT2AMAPTHPGD | |
| SCHEMBL1852796 | 0.78 | SMN1; SMN2 (0.74) | SMN1; SMN2LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL6662121 | 0.78 | KMT2A (0.76) | LMNAKMT2ASLC6A2SLC6A3TDP1 | |
| SCHEMBL14798952 | 0.76 | POLB (0.57) | SMN1; SMN2LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL27968711 | 0.75 | ALDH1A1 (0.56) | SMN1; SMN2KMT2AHPGDALDH1A1L3MBTL1 | |
| SCHEMBL380710 | 0.73 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL16585699 | 0.73 | CA1 (0.72) | SMN1; SMN2LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL28163544 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL29317291 | 0.72 | KMT2A (0.53) | SMN1; SMN2LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL7945249 | 0.72 | ESR2 (0.57) | SMN1; SMN2LMNAKMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827088-A | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMA SPA | 2014-05-28 | — | — | CN | disclosed |