Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28122542 | 0.83 | ALDH1A1 (0.43) | KMT2ATSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL27396814 | 0.80 | NR4A2 (0.41) | KMT2AALDH1A1HSD17B10KDM4EATM | |
| SCHEMBL29408467 | 0.79 | KMT2A (0.67) | KMT2ATSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL43644 | 0.79 | KMT2A (0.67) | KMT2ATSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL4444645 | 0.79 | KMT2A (0.67) | KMT2ATSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL29271836 | 0.78 | KMT2A (0.65) | KMT2ATSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL30492227 | 0.77 | KMT2A (0.64) | KMT2ATSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL13066502 | 0.77 | KMT2A (0.64) | KMT2ATSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL28409026 | 0.75 | KMT2A (0.61) | KMT2ATSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL25271509 | 0.74 | KMT2A (0.53) | KMT2ATSHRLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103827088-B | It is used as the derivative of the pyridyl alkyl alcohol of 1 phenyl 2 of phosphodiesterase inhibitors | 奇斯药制品公司 | 2017-10-13 | — | — | CN | disclosed |
| CN-103827088-A | Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors | CHIESI FARMA SPA | 2014-05-28 | — | — | CN | disclosed |