SCHEMBL43644

SCHEMBL43644

COC(=O)c1ccccc1N(C)C

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
ALDH1A1 P00352 4/20 0.64
TSHR P16473 3/20 0.64
MAPT P10636 2/20 0.64
GAA P10253 2/20 0.64
TP53 P04637 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
LMNA P02545 2/20 0.57
HSD17B10 Q99714 2/20 0.55
CFTR P13569 1/20 0.55
KDM4E B2RXH2 3/20 0.53
POLB P06746 1/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.51
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA5A P35218 1/20 0.49
CA9 Q16790 1/20 0.49
ALOX15 P16050 1/20 0.49
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408467 1.00 KMT2A (0.67) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL4444645 0.88 KMT2A (0.67) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL29271836 0.86 KMT2A (0.65) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL30492227 0.86 KMT2A (0.64) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL13066502 0.86 KMT2A (0.64) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL9550019 0.86 TSHR (0.67) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL24572151 0.83 KMT2A (0.53) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL28409026 0.83 KMT2A (0.61) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL21775802 0.83 KMT2A (0.53) KMT2AALDH1A1TSHRMAPTGAA
SCHEMBL2427326 0.83 KMT2A (0.53) KMT2AALDH1A1TSHRMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 579 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260033492-A1 Pest Repellents and Uses Thereof SENSORYGEN INC (US) 2026-02-05 US claimed
US-20250017954-A1 Formulations and Methods for Treating Symptoms of Menopause Kindra Corporation (US) 2025-01-16 US claimed
US-20240365792-A1 Pest Control Formulations and Uses Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-11-07 US claimed
EP-4433045-A2 FORMULATIONS AND METHODS FOR TREATING SYMPTOMS OF MENOPAUSE KINDRA CORPORATION (US) 2024-09-25 EP claimed
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO claimed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US claimed
CN-118510501-A Formulations and methods for treating climacteric symptoms 金卓拉公司 2024-08-16 CN claimed
EP-4395547-A1 PEST CONTROL FORMULATIONS AND USES THEREOF Sensorygen, Inc. (US) 2024-07-10 EP claimed
CN-118184520-A Biphenyl amine compound, preparation method thereof and application thereof in flow battery 中国科学院大连化学物理研究所 2024-06-14 CN claimed
CN-117064765-B Dental adhesive restorative material composition and application thereof 长春新斯达科技有限公司 2023-12-29 CN claimed
US-20160137587-A1 TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-05-19 US claimed
EP-3013787-A1 TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES Council of Scientific & Industrial Research (IN) 2016-05-04 EP claimed
US-20150126437-A1 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-05-07 US claimed
WO-2014207761-A1 TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-12-31 WO claimed
EP-2775839-A2 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS The Regents of The University of California (US) 2014-09-17 EP claimed
WO-2013059364-A2 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-04-25 WO claimed
US-20070184353-A1 Volume hologram recording material and volume hologram recording medium TOAGOSEI CO., LTD. (JP) 2007-08-09 US claimed
EP-1729184-A1 VOLUME HOLOGRAM RECORDING MATERIAL AND VOLUME HOLOGRAM RECORDING MEDIUM TOAGOSEI CO., LTD. (JP) 2006-12-06 EP claimed
US-5508180-A OXIDATION OF SULFIDES; DEALKYLATION OF ETHERS, AMINES; HALOGENATION; POLYMERIZATION ENZYMOL INTERNATIONAL, INC. 1996-04-16 US claimed
US-4297380-A WHEREIN METHYL ANTHRANILATE IS USED AS AN AROMATIZING AGENT SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) 1981-10-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF L3MBTL4, L3MBTL3, L3MBTL1 KMT2A 404/4885ALDH1A1 3333/4885TSHR 3541/4885
US-20240365792-A1 Pest Control Formulations and Uses Thereof ACHE, DDT, BCHE KMT2A 700/4885ALDH1A1 3068/4885TSHR 3899/4885
US-20260033492-A1 Pest Repellents and Uses Thereof F3, TFPI, FLI1 KMT2A 1811/4885ALDH1A1 1128/4885TSHR 1078/4885
US-20160137587-A1 TRANSITION-METAL-FREE N-ARYLATION OF TERTIARY AMINES USING ARYNES CDK6, NEK6, MCM6 KMT2A 156/4885ALDH1A1 1357/4885TSHR 1941/4885
US-20150126437-A1 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS CHIA, C5AR1, CHI3L1 KMT2A 3122/4885ALDH1A1 3190/4885TSHR 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.