Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27968956 | 0.85 | LMNA (0.52) | KDM2BLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL27968966 | 0.84 | KDM2B (0.49) | KDM2BLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL10413533 | 0.82 | CYP1A2 (0.61) | KDM2BLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL14638477 | 0.80 | ALDH1A1 (0.60) | KDM2BLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL21381748 | 0.80 | ALDH1A1 (0.60) | KDM2BLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL1291777 | 0.79 | PDE4B (0.66) | KDM2BLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL15684713 | 0.78 | PDE4B (0.64) | KDM2BLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL28853734 | 0.78 | SLC18A3 (0.57) | KDM2BLMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14637151 | 0.77 | KDM2B (0.58) | KDM2BLMNAPKMKDM4EALDH1A1 | |
| SCHEMBL8948042 | 0.76 | MEN1 (0.58) | KDM2BLMNAPKMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103781776-A | Novel 2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors | NOVARTIS AG | 2014-05-07 | — | — | CN | disclosed |