SCHEMBL279696

SCHEMBL279696

O=Cc1ccc2cccc(O)c2n1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.64
CCR1 P32246 1/20 0.63
CD74 P04233 1/20 0.58
MIF P14174 1/20 0.58
KMT2A Q03164 11/20 0.55
MEN1 O00255 9/20 0.55
NPC1 O15118 9/20 0.55
RAB9A P51151 8/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
POLB P06746 1/20 0.55
MAPT P10636 4/20 0.54
HTT P42858 4/20 0.54
HSP90AA1 P07900 3/20 0.54
AGTR1 P30556 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
METAP2 P50579 1/20 0.53
PLAU P00749 1/20 0.53
NCF1 P14598 1/20 0.53
ALDH1A1 P00352 1/20 0.52
CYP1A2 P05177 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29406155 1.00 KDM4E (0.64) KDM4ECCR1CD74MIFKMT2A
SCHEMBL29694379 1.00 KDM4E (0.64) KDM4ECCR1CD74MIFKMT2A
SCHEMBL28508815 0.98 KDM4E (0.62) KDM4ECCR1CD74MIFKMT2A
SCHEMBL29783026 0.98 KDM4E (0.62) KDM4ECCR1CD74MIFKMT2A
SCHEMBL28500579 0.98 KDM4E (0.62) KDM4ECCR1CD74MIFKMT2A
SCHEMBL31157804 0.98 KDM4E (0.62) KDM4ECCR1CD74MIFKMT2A
SCHEMBL28507863 0.98 KDM4E (0.62) KDM4ECCR1CD74MIFKMT2A
SCHEMBL29926750 0.98 KDM4E (0.62) KDM4ECCR1CD74MIFKMT2A
SCHEMBL28904663 0.98 KDM4E (0.62) KDM4ECCR1CD74MIFKMT2A
Cyclohexylamine SCHEMBL7792748 0.85 KDM4E (0.49) KDM4ECCR1CD74MIFKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081857-A Serial binuclear dysprosium complex constructed based on salicylaldehyde derivative condensed methoxy acetic acid hydrazine Schiff base ligand and synthesis method thereof 广西师范大学 2025-06-03 CN claimed
CN-119932669-A Preparation method of 6063 aluminum alloy self-sealing micro-arc oxidation ceramic film 常州工学院 2025-05-06 CN claimed
CN-116239590-B Preparation method and application of novel fluorescent probe for identifying cadmium ions 右江民族医学院 2025-04-15 CN claimed
CN-119462769-A Preparation method and application of bimodal linear polyethylene chromium carbene catalyst 西北大学 2025-02-18 CN claimed
CN-119241599-A Platinum complex of 8-hydroxyquinoline derivative and synthetic method and application thereof 玉林师范学院 2025-01-03 CN claimed
CN-119241597-A Platinum complex of 8-hydroxyquinoline derivative and synthetic method and application thereof 玉林师范学院 2025-01-03 CN claimed
CN-118847623-A Surface treatment device, surface treatment method of display substrate and display device 京东方科技集团股份有限公司 2024-10-29 CN claimed
CN-118437610-A Corrosion-resistant low-carbon steel pipe and preparation method thereof 淮安市逸臣精密机械有限公司 2024-08-06 CN claimed
CN-118084781-A Zirconium-ion fluorescence probe of hydroxyquinoline disulfide and preparation method thereof 南昌航空大学 2024-05-28 CN claimed
CN-117964645-A Synthesis method and application of 8-hydroxyquinoline aldehyde N-O pyridine bisacylhydrazone tetranuclear dysprosium cluster compound 广西医科大学 2024-05-03 CN claimed
CN-104629753-A Thia-calyx [4] arene fluorescent reagent with selective bonding La<3+>lu<3+>, synthesis and application UNIV GUIZHOU 2015-05-20 CN claimed
EP-2188259-B1 QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS UNIV HONG KONG POLYTECHNIC (CN) 2013-11-06 EP claimed
CN-101868447-A Methods of making and administering quinoline derivatives as anticancer agents UNIV HONG KONG POLYTECHNIC 2010-10-20 CN claimed
WO-2009024095-A1 METHOD OF MAKING AND ADMINISTERING QUINOLINE DERIVATIVES AS ANTI-CANCER AGENTS THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2009-02-26 WO claimed
US-20090054482-A1 Method of making and administering quinoline derivatives as anti-cancer agents THE HONG KONG POLYTECHNIC UNIVERSITY (HK) 2009-02-26 US claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 KDM4E 440/4885CCR1 4620/4885CD74 1184/4885
US-20090054482-A1 Method of making and administering quinoline derivatives as anti-cancer agents HCCS, GLS2, NQO1 KDM4E 1265/4885CCR1 3546/4885CD74 3914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.