NDUFB5 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20
SCHEMBL8490937	0.53	3/20

Clinical trials — most relevant to NDUFB5 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN
A RETROspective Study of Patients With TK2d	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy	nan	COMPLETED
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis	nan	COMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a NDUFB5 binder may also engage these)

Protein	Name	Similarity
Q0MQD8	—	1.000	Q0MQD8 →
Q02380	—	1.000	Q02380 →
Q0MQD7	—	1.000	Q0MQD7 →
Q9CQH3	—	1.000	Q9CQH3 →
Q0MQD6	—	1.000	Q0MQD6 →
Q4R4E0	—	1.000	Q4R4E0 →
Q4QQV3	—	0.987	Q4QQV3 →
Q9D6U8	—	0.986	Q9D6U8 →
Q0MQC7	—	0.985	Q0MQC7 →
Q0MQJ3	—	0.985	Q0MQJ3 →
O93980	—	0.981	O93980 →
Q7JX57	—	0.980	Q7JX57 →
Q2NKR7	—	0.980	Q2NKR7 →
NDUFB11	NADH dehydrogenase [ubiquinone] 1 beta subcom	0.980	landscape →
Q0MQJ4	—	0.980	Q0MQJ4 →
Q9HD33	—	0.980	Q9HD33 →
A3KP48	—	0.980	A3KP48 →
O74988	—	0.980	O74988 →
Q9W549	—	0.980	Q9W549 →
Q8HXG5	—	0.979	Q8HXG5 →
P82649	—	0.979	P82649 →
Q0MQC9	—	0.979	Q0MQC9 →
D6X268	—	0.979	D6X268 →
Q0MQC8	—	0.979	Q0MQC8 →
Q8RWA7	—	0.979	Q8RWA7 →
P0CB69	—	0.979	P0CB69 →
FAM162A	Protein FAM162A	0.979	landscape →
Q3UIU2	—	0.979	Q3UIU2 →
O09111	—	0.979	O09111 →
Q9D6J5	—	0.979	Q9D6J5 →