NDUFB7 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8492838	0.52	4/20
SCHEMBL8492845	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
SCHEMBL8494171	0.50	4/20
SCHEMBL8494175	0.50	4/20
SCHEMBL8494177	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20

Clinical trials — most relevant to NDUFB7 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Clinical Evaluation of the Effect of Metformin in Sepsis	PHASE3	UNKNOWN
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)	PHASE3	WITHDRAWN
Coenzyme Q10 as a Symptomatic Treatment in Parkinson's Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome	PHASE1/PHASE2	COMPLETED
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Parkinson's Disease Treatment With Coenzyme Q10	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Nicotinamide Riboside in Ulcerative Colitis	nan	RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Paediatric Obesity and Cardiovascular Dysfunction	nan	COMPLETED
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis	nan	COMPLETED
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome	nan	COMPLETED
Gastrointestinal Dysfunction in Children Affected With Mitochondrial Disorders	nan	COMPLETED
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN
Effect of Diaphragm Stimulation During Surgery	nan	COMPLETED
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a NDUFB7 binder may also engage these)

Protein	Name	Similarity
Q02368	—	1.000	Q02368 →
Q0MQE4	—	1.000	Q0MQE4 →
Q0MQE2	—	1.000	Q0MQE2 →
Q0MQE3	—	1.000	Q0MQE3 →
Q9CR61	—	1.000	Q9CR61 →
Q552P9	—	0.989	Q552P9 →
B3LQW4	—	0.988	B3LQW4 →
P90789	—	0.988	P90789 →
A6ZZI5	—	0.987	A6ZZI5 →
P36064	—	0.987	P36064 →
Q54V61	—	0.987	Q54V61 →
O74347	—	0.986	O74347 →
Q9SKC9	—	0.986	Q9SKC9 →
Q3E7A4	—	0.982	Q3E7A4 →
Q6BKN1	—	0.981	Q6BKN1 →
Q9UTC2	—	0.981	Q9UTC2 →
Q02373	—	0.980	Q02373 →
G2TRU5	—	0.979	G2TRU5 →
Q9DCS9	—	0.979	Q9DCS9 →
O75012	—	0.978	O75012 →
Q17Q91	—	0.977	Q17Q91 →
Q8SPI2	—	0.977	Q8SPI2 →
Q02772	—	0.976	Q02772 →
Q28GG4	—	0.976	Q28GG4 →
Q9BUK0	—	0.976	Q9BUK0 →
Q9BYN8	—	0.976	Q9BYN8 →
Q0UWF1	—	0.976	Q0UWF1 →
Q0MQF0	—	0.976	Q0MQF0 →
Q0MQF3	—	0.976	Q0MQF3 →
Q1K5Z0	—	0.976	Q1K5Z0 →