SCHEMBL27969720

SCHEMBL27969720

O=C(OCc1ccc2c(c1)OCO2)[C@H](O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.62
EDNRA P25101 3/20 0.59
FAAH O00519 1/20 0.54
MGLL Q99685 1/20 0.54
ALDH1A1 P00352 5/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
TSHR P16473 2/20 0.52
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
TP53 P04637 1/20 0.52
MAPT P10636 1/20 0.52
ATM Q13315 1/20 0.52
KMT2A Q03164 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
HTT P42858 2/20 0.50
NAAA Q02083 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
ACE P12821 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27969666 1.00 CYP3A4 (0.62) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL7993756 0.81 ACE (0.53) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL31171631 0.81 ACE (0.58) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL31171638 0.81 ACE (0.58) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL31053868 0.80 CYP3A4 (0.77) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL1171492 0.80 CYP3A4 (0.77) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL786608 0.80 CYP3A4 (0.53) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL7990089 0.79 EDNRA (0.60) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL28867473 0.77 CYP3A4 (0.53) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL306160 0.77 CYP3A4 (1.00) CYP3A4FAAHMGLLALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103923056-B The synthetic method of Heliotropin CHENGDU JIANZHONG FLAVORS & FRAGRANCES CO., LTD. (CN) 2016-05-25 CN claimed
CN-103923056-B The synthetic method of Heliotropin CHENGDU JIANZHONG FLAVORS & FRAGRANCES CO., LTD. (CN) 2016-05-25 CN disclosed
CN-103923056-B The synthetic method of Heliotropin CHENGDU JIANZHONG FLAVORS & FRAGRANCES CO., LTD. (CN) 2016-05-25 CN disclosed
CN-103923056-A Synthetic method of 3, 4-methylene dioxybenzaldehyde CHENGDU JIANZHONG FLAVORS & FRAGRANCES CO LTD 2014-07-16 CN disclosed