SCHEMBL786608

SCHEMBL786608

O=C(CBr)OC(C(=O)OCc1ccc2c(c1)OCO2)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.53
EDNRA P25101 3/20 0.53
FAAH O00519 1/20 0.50
MGLL Q99685 1/20 0.50
ALDH1A1 P00352 4/20 0.46
TSHR P16473 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
TP53 P04637 1/20 0.46
MAPT P10636 1/20 0.46
ATM Q13315 1/20 0.46
HTT P42858 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
ACE P12821 1/20 0.43
HRH4 Q9H3N8 1/20 0.43
CHRM5 P08912 2/20 0.43
CHRM1 P11229 2/20 0.43
CHRM2 P08172 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27969666 0.80 CYP3A4 (0.62) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL27969720 0.80 CYP3A4 (0.62) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL803787 0.75 EDNRA (0.56) CYP3A4EDNRASMN1; SMN2NPC1RAB9A
SCHEMBL31053868 0.74 CYP3A4 (0.77) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL1171492 0.74 CYP3A4 (0.77) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL29067208 0.72 CYP3A4 (0.74) CYP3A4FAAHMGLLALDH1A1TSHR
SCHEMBL7993756 0.72 ACE (0.53) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL31171638 0.72 ACE (0.58) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL31171631 0.72 ACE (0.58) CYP3A4EDNRAFAAHMGLLALDH1A1
SCHEMBL29067211 0.72 CYP3A4 (0.68) CYP3A4EDNRAFAAHMGLLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785655-B2 Ionic liquid solvents DUBLIN CITY UNIVERSITY (IE) 2014-07-22 US disclosed
US-20120071661-A1 Ionic Liquid Solvents DUBLIN CITY UNIVERSITY (IE) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071661-A1 Ionic Liquid Solvents EBP, PAICS, HACD3 CYP3A4 452/4885EDNRA 3492/4885FAAH 1357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.