Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970939 | 0.99 | FABP4 (0.45) | FABP4FABP5TDP1L3MBTL1ADORA1 | |
| SCHEMBL27971069 | 0.84 | FABP4 (0.36) | FABP4FABP5ACMSDDHODH | |
| SCHEMBL28813996 | 0.84 | ACMSD (0.39) | ADORA1ADORA2AACMSDRAPGEF4 | |
| SCHEMBL14916294 | 0.81 | FABP4 (0.57) | FABP4FABP5TDP1L3MBTL1ADORA1 | |
| SCHEMBL14916710 | 0.81 | FABP4 (0.43) | FABP4FABP5TDP1L3MBTL1ADORA1 | |
| SCHEMBL14916476 | 0.80 | ESR1 (0.41) | FABP4FABP5TDP1L3MBTL1ADORA1 | |
| SCHEMBL27541155 | 0.79 | ADORA2A (0.47) | ADORA1ADORA2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14916539 | 0.78 | FABP4 (0.58) | FABP4FABP5ADORA1ADORA2AALDH1A1 | |
| SCHEMBL14916692 | 0.78 | FABP4 (0.43) | FABP4FABP5TDP1L3MBTL1ADORA1 | |
| SCHEMBL14916989 | 0.77 | FABP4 (0.42) | FABP4FABP5TDP1L3MBTL1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906735-A | Novel aryl-quinoline derivatives | HOFFMANN LA ROCHE | 2014-07-02 | — | — | CN | disclosed |