Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796011 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL3260254 | 0.84 | ORAI1 (0.38) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL2795766 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL10621746 | 0.75 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL9300908 | 0.75 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL9301152 | 0.72 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL3258768 | 0.72 | LMNA (0.35) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL13232459 | 0.72 | KDM4E (0.52) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL9299699 | 0.71 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL10617852 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167931-A1 | HETEROCYCLICALLY SUBSTITUTED HETEROCYCLYLCARBOXYLIC ACID DERIVATIVES | HPD, HAAO, HCAR2 | KDM4E 1581/4885ALDH1A1 475/4885HSD17B10 736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.