⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1352854 | 0.94 | — | — | |
| SCHEMBL18600046 | 0.92 | ALDH1A1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL8903575 | 0.90 | ALDH1A1 (0.33) | — | |
| SCHEMBL14151912 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL25278636 | 0.86 | — | — | |
| SCHEMBL24734673 | 0.73 | CYP2D6 (0.38) | — | |
| SCHEMBL13798801 | 0.73 | ROCK2 (0.31) | — | |
| SCHEMBL2656497 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL2656499 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL15160716 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103880768-B | A kind of chemical synthesis process of 3-cyclobutyl morpholine | NANTONG UNIVERSITY (CN) | 2016-04-13 | — | — | CN | claimed |
| EP-4648853-A1 | TARGETED DEGRADATION OF VAV1 | Monte Rosa Therapeutics AG (CH) | 2025-11-19 | — | — | EP | disclosed |
| US-12257247-B2 | Targeted degradation of VAV1 | MONTE ROSA THERAPEUTICS AG (CH) | 2025-03-25 | — | — | US | disclosed |
| US-20240285604-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS AG (CH) | 2024-08-29 | — | — | US | disclosed |
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| WO-2024151547-A1 | TARGETED DEGRADATION OF VAV1 | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-07-18 | — | — | WO | disclosed |
| CN-103880768-B | A kind of chemical synthesis process of 3-cyclobutyl morpholine | NANTONG UNIVERSITY (CN) | 2016-04-13 | — | — | CN | disclosed |
| CN-103880768-B | A kind of chemical synthesis process of 3-cyclobutyl morpholine | NANTONG UNIVERSITY (CN) | 2016-04-13 | — | — | CN | disclosed |
| CN-103880768-A | Chemical synthesis method of 3-cyclobutylmorpholine | UNIV NANTONG | 2014-06-25 | — | — | CN | disclosed |