Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40857 | 0.84 | LOXL2 (0.67) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL1198560 | 0.82 | CYP4F2 (0.59) | LOXL2CYP4F2CYP4A11ALDH1A1MEN1 | |
| SCHEMBL27543741 | 0.80 | FOLH1 (0.58) | KMT2AFOLH1 | |
| SCHEMBL27971856 | 0.78 | LOXL2 (0.53) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL27962222 | 0.77 | LOXL2 (0.47) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL28002924 | 0.76 | CYP4F2 (0.53) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL1116172 | 0.75 | ATM (0.46) | LOXL2CYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL27986137 | 0.74 | CYP4F2 (0.55) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL28813161 | 0.73 | MEN1 (0.48) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 | |
| SCHEMBL27944407 | 0.73 | LOXL2 (0.44) | LOXL2CYP4F2CYP4A11SLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958487-A | Benzoic acid derivatives as eif4e inhibitors | HOFFMANN LA ROCHE | 2014-07-30 | — | — | CN | disclosed |