Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13948877 | 0.85 | CFTR (0.51) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL14860095 | 0.82 | CES2 (0.41) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL16723454 | 0.81 | ALDH1A1 (0.48) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL107636 | 0.80 | CSNK2A1 (0.52) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL28471721 | 0.80 | CES2 (0.48) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL7787350 | 0.79 | CES2 (0.47) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL4620600 | 0.77 | CES2 (0.46) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL108796 | 0.77 | SMN1; SMN2 (0.47) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL5655447 | 0.77 | CES2 (0.37) | CES2SMN1; SMN2TP53MAPTRAB9A | |
| SCHEMBL27155937 | 0.77 | KMT2A (0.47) | SMN1; SMN2TP53MAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101910168-B | Tropane compounds | EXELIXIS INC | 2014-07-30 | — | — | CN | disclosed |