Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24810096 | 0.81 | HTR2A (0.41) | ALDH1A1HPGDLMNAGLACYP2C9 | |
| SCHEMBL27973185 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TSHRHPGDLMNAGLA | |
| SCHEMBL9936557 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRHPGDLMNAGLA | |
| SCHEMBL30275153 | 0.81 | TSHR (0.51) | MPLALDH1A1TSHRHPGDLMNA | |
| SCHEMBL9937126 | 0.81 | TSHR (0.51) | MPLALDH1A1TSHRHPGDLMNA | |
| SCHEMBL27972984 | 0.80 | KDM4E (0.44) | MPLALDH1A1TSHRHPGDLMNA | |
| SCHEMBL8127712 | 0.80 | HTR2A (0.40) | MAPTMEN1KMT2AGAATDP1 | |
| Hydrochloric Acid SCHEMBL2913110 | 0.79 | HPGD (0.41) | MPLALDH1A1TSHRHPGDLMNA | |
| SCHEMBL6287419 | 0.77 | HTR2A (0.58) | MPLALDH1A1TSHRHPGDLMNA | |
| SCHEMBL22803765 | 0.77 | HTR2A (0.41) | ALDH1A1TSHRMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102970869-B | Indoles | GLAXOSMITHKLINE LLC | 2014-07-16 | — | — | CN | disclosed |