Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27970716 | 0.87 | KDM1A (0.37) | KDM1AALDH1A1MAPTSLC6A2MAOB | |
| SCHEMBL2564602 | 0.87 | KDM1A (0.37) | KDM1ANTMT1RORCALDH1A1SLC6A2 | |
| SCHEMBL27706519 | 0.87 | TACR1 (0.42) | KDM1ASMN1; SMN2SLC6A2TACR1 | |
| SCHEMBL28271460 | 0.87 | SLC6A4 (0.40) | SLC6A2 | |
| SCHEMBL27891314 | 0.87 | KDM1A (0.51) | KDM1ARORCALDH1A1GAASMN1; SMN2 | |
| SCHEMBL14673029 | 0.86 | KDM1A (0.36) | KDM1ANTMT1RORCGFERSMN1; SMN2 | |
| SCHEMBL27970723 | 0.83 | SMN1; SMN2 (0.43) | TSHRKDM1AALDH1A1KDM4EMAPT | |
| SCHEMBL14673009 | 0.82 | NPC1 (0.41) | ALDH1A1MAPTSMN1; SMN2CYP2C19 | |
| SCHEMBL6249889 | 0.81 | KDM1A (0.42) | KDM1ADEGS1 | |
| SCHEMBL31727845 | 0.80 | KDM1A (0.36) | KDM1AALDH1A1KDM4EMAPTSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107417549-A | As LSD1 inhibitor（It is miscellaneous）Aryl cyclopropyl amines | 奥莱松基因组股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-103958474-B | (hetero) arylcyclopropylamine compounds as LSD1 inhibitors | 奥莱松基因组股份有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-103958474-A | (hetero) arylcyclopropylamine compounds as LSD1 inhibitors | ORYZON GENOMICS SA | 2014-07-30 | — | — | CN | disclosed |