Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24658450 | 0.84 | KDM1A (0.44) | KDM1ALMNA | |
| SCHEMBL3170686 | 0.84 | SMN1; SMN2 (0.50) | KDM1ASLC18A3 | |
| SCHEMBL6249011 | 0.83 | GABRA1 (0.52) | KDM1AGABRA1GABRB2 | |
| SCHEMBL28695022 | 0.82 | KDM1A (0.46) | KDM1ADEGS1ESR2 | |
| SCHEMBL28695021 | 0.82 | KDM1A (0.46) | KDM1ADEGS1ESR2 | |
| SCHEMBL28829894 | 0.81 | SLC6A2 (0.47) | KDM1ALMNA | |
| SCHEMBL27973992 | 0.81 | TSHR (0.38) | KDM1ADEGS1 | |
| SCHEMBL24658425 | 0.75 | CA1 (0.40) | — | |
| SCHEMBL28377084 | 0.74 | KDM1A (0.44) | KDM1AGABRA1GABRB2CHRM2CHRM4 | |
| SCHEMBL21236176 | 0.73 | KDM1A (0.53) | KDM1AGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051904-A2 | NOVEL PROCESSES FOR THE SYNTHESIS OF CYCLOPROPYL COMPOUNDS | PHARMACIA CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |