Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indene SCHEMBL6273661 | 0.89 | CYP2D6 (0.45) | CYP2D6CYP2C19CA1CA2SMN1; SMN2 | |
| Indene SCHEMBL31277557 | 0.89 | CYP2D6 (0.45) | CYP2D6CYP2C19CA1CA2SMN1; SMN2 | |
| Indene SCHEMBL28193236 | 0.85 | CA1 (0.46) | CYP2D6CYP2C19CA1CA2SMN1; SMN2 | |
| Indene SCHEMBL28869263 | 0.85 | CYP2D6 (0.49) | CYP2D6CYP2C19CA1CA2SMN1; SMN2 | |
| Indene SCHEMBL6268710 | 0.83 | CYP2D6 (0.39) | CYP2D6CYP2C19CA1CA2SMN1; SMN2 | |
| Indene SCHEMBL29746662 | 0.83 | CYP2D6 (0.51) | CYP2D6CYP2C19CA1CA2MTNR1A | |
| Indene SCHEMBL89373 | 0.83 | CYP2D6 (0.51) | CYP2D6CYP2C19CA1CA2MTNR1A | |
| Indene SCHEMBL6700608 | 0.83 | CA2 (0.47) | CYP2D6CYP2C19CA1CA2HSD17B3 | |
| Indene SCHEMBL30959780 | 0.83 | CA2 (0.47) | CYP2D6CYP2C19CA1CA2HSD17B3 | |
| Indene SCHEMBL28216169 | 0.82 | CA1 (0.50) | CYP2D6CYP2C19CA1CA2HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107325128-B | A kind of preparation method of DiDOPO class compound | 中国科学院宁波材料技术与工程研究所 | 2019-04-02 | — | — | CN | claimed |
| CN-107325128-A | A kind of preparation method of DiDOPO classes compound | 中国科学院宁波材料技术与工程研究所 | 2017-11-07 | — | — | CN | claimed |
| CN-107325128-B | A kind of preparation method of DiDOPO class compound | 中国科学院宁波材料技术与工程研究所 | 2019-04-02 | — | — | CN | disclosed |
| CN-107325128-A | A kind of preparation method of DiDOPO classes compound | 中国科学院宁波材料技术与工程研究所 | 2017-11-07 | — | — | CN | disclosed |
| CN-104119673-A | Halogen-free flame-retardant high-temperature nylon | NINGBO INST MATERIALS TECHNOLOGY & ENG CAS | 2014-10-29 | — | — | CN | disclosed |
| CN-104086593-A | DOPO derivatives, preparation method and application thereof | NINGBO INST MATERIALS TECHNOLOGY & ENG CAS | 2014-10-08 | — | — | CN | disclosed |