Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 2/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27779727 | 0.92 | PNP (0.43) | PNPDPP4PDPK1GDAALDH1A1 | |
| Phosphoric Acid SCHEMBL27780172 | 0.92 | PNP (0.43) | PNPDPP4PDPK1GDAALDH1A1 | |
| SCHEMBL41788 | 0.81 | PNP (0.50) | PNPDPP4PDPK1GDAALDH1A1 | |
| SCHEMBL2983851 | 0.79 | PNP (0.49) | PNPDPP4PDPK1GDAALDH1A1 | |
| SCHEMBL1843777 | 0.79 | PNP (0.49) | PNPDPP4PDPK1GDAALDH1A1 | |
| SCHEMBL2051365 | 0.79 | PNP (0.49) | PNPDPP4PDPK1GDAALDH1A1 | |
| SCHEMBL8886040 | 0.79 | PNP (0.49) | PNPDPP4PDPK1GDAALDH1A1 | |
| SCHEMBL20579 | 0.79 | DPP4 (0.50) | PNPDPP4PDPK1GDAALDH1A1 | |
| SCHEMBL20867 | 0.79 | ATAD2 (0.53) | PNPDPP4PDPK1GDALMNA | |
| SCHEMBL852108 | 0.79 | PNP (0.49) | PNPDPP4PDPK1GDAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119265192-A | Compound of modified nucleotide monomer and application of compound in RNAi (ribonucleic acid interference) medicament | 纳肽得(青岛)生物医药有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-118834250-A | Novel delivery vehicle | 纳肽得(青岛)生物医药有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118834255-A | Novel modified nucleotide and application thereof in RNAi (ribonucleic acid interference) medicament | 纳肽得(青岛)生物医药有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118813612-A | Application of compound in RNAi (ribonucleic acid interference) medicament | 纳肽得(青岛)生物医药有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-117737057-A | Small nucleic acid sequence with enhanced anti-hepatitis B effect and conjugate thereof | 纳肽得(青岛)生物医药有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117363614-A | SiRNA for inhibiting expression of angiotensinogen and application thereof | 纳肽得(青岛)生物医药有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117363615-A | SiRNA for inhibiting complement C5 expression and application thereof | 纳肽得(青岛)生物医药有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-114401736-A | PALM for the treatment of chemotherapy-induced peripheral neuropathy occurring with cancer treatment | 佩蒂诺沃生物制药公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-113710671-A | Cyclic molecules as inhibitors of bruton's tyrosine kinase | 明慧医药（上海）有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-112739359-A | APMV and its use for the treatment of cancer | 西奈山伊坎医学院 | 2021-04-30 | — | — | CN | disclosed |
| CN-112533581-A | PRC1 inhibitors and methods of treatment therewith | 密歇根大学董事会 | 2021-03-19 | — | — | CN | disclosed |
| CN-110642910-B | Thymidine derivative and preparation method and application thereof | 南开大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-110642910-A | Thymidine derivative and preparation method and application thereof | 南开大学 | 2020-01-03 | — | — | CN | disclosed |
| CN-103974724-A | Modified nucleosides, nucleotides and nucleic acids and uses thereof | modeRNA Therapeutics | 2014-08-06 | — | — | CN | disclosed |