SCHEMBL279773

SCHEMBL279773

O=C1NCCCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821040 0.96 CRBN (0.50)
SCHEMBL1955052 0.96 CRBN (0.50)
SCHEMBL8089176 0.96 CRBN (0.50)
SCHEMBL540697 0.96
Hydrochloric Acid SCHEMBL11629900 0.96
SCHEMBL820531 0.96 CRBN (0.50)
SCHEMBL820756 0.96 CRBN (0.50)
SCHEMBL820411 0.96 CRBN (0.50)
SCHEMBL21423158 0.96 CRBN (0.50)
SCHEMBL820984 0.96 CRBN (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3730527-B1 PROCESS FOR THE PREPARATION OF A REACTION PRODUCT OF A CYCLIC UREA AND A MULTIFUNCTIONAL ALDEHYDE ALLNEX NETHERLANDS BV (NL) 2023-07-05 EP claimed
EP-4019563-A1 FORMALDEHYDE FREE CROSSLINKING COMPOSITIONS Allnex Netherlands B.V. (NL) 2022-06-29 EP claimed
EP-3966206-A1 HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF Deciphera Pharmaceuticals, LLC (US) 2022-03-16 EP claimed
CN-114127057-A Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof 德西费拉制药有限责任公司 2022-03-01 CN claimed
CN-114072397-A Heteroaryl aminopyrimidine amide autophagy inhibitors and methods of use thereof 德西费拉制药有限责任公司 2022-02-18 CN claimed
US-11124606-B2 Formaldehyde free crosslinking compositions ALLNEX NETHERLANDS B.V. (NL) 2021-09-21 US claimed
WO-2020231808-A1 HETEROARYLAMINOPYRIMIDINE AMIDE AUTOPHAGY INHIBITORS AND METHODS OF USE THEREOF DECIPHERA PHARMACEUTICALS, LLC (US) 2020-11-19 WO claimed
EP-3730527-A1 PROCESS FOR THE PREPARATION OF A REACTION PRODUCT OF A CYCLIC UREA AND A MULTIFUNCTIONAL ALDEHYDE Allnex Netherlands B.V. (NL) 2020-10-28 EP claimed
EP-2621975-B1 PROCESS FOR THE PREPARATION OF A REACTION PRODUCT OF A CYCLIC UREA AND A MULTIFUNCTIONAL ALDEHYDE ALLNEX NETHERLANDS BV (NL) 2020-07-01 EP claimed
US-10457776-B2 Formaldehyde free crosslinking compositions ALLNEX NETHERLANDS B.V. (NL) 2019-10-29 US claimed
US-20090104116-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2009-04-23 US claimed
EP-1979342-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF Jerini AG (DE) 2008-10-15 EP claimed
US-20080139777-A1 Amide/urea-modified liquid diphenylmethane diisocyanates BAYER MATERIALSCIENCE LLC 2008-06-12 US claimed
WO-2008060454-A2 AMIDE/UREA-MODIFIED LIQUID DIPHENYLMETHANE DIISOCYANATES BAYER MATERIALSCIENCE LLC (US) 2008-05-22 WO claimed
WO-2007088041-A1 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF JERINI AG (DE) 2007-08-09 WO claimed
US-5206328-A Disproportionation equilibration reaction between an epoxy containing siloxane and an epoxyless siloxane in an aprotic solvent using a basic catalyst; no epoxy ring opening SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-04-27 US claimed
US-4374135-A AMIDINO HYDRAZONE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1983-02-15 US claimed
US-4260652-A POLYBENZIMIDAZOLONES TEIJIN LIMITED (JP) 1981-04-07 US claimed
US-4154931-A Process for the preparation of cyclic ureas THE UPJOHN COMPANY (US) 1979-05-15 US claimed
US-4087525-A Pentadienone hydrazones as insecticides AMERICAN CYANAMID COMPANY (US) 1978-05-02 US claimed