Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.50 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21423158 | 1.00 | CRBN (0.50) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL820756 | 1.00 | CRBN (0.50) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL820984 | 1.00 | CRBN (0.50) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL540697 | 1.00 | — | — | |
| SCHEMBL1955052 | 1.00 | CRBN (0.50) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL821040 | 1.00 | CRBN (0.50) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL8089176 | 1.00 | CRBN (0.50) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL820411 | 1.00 | CRBN (0.50) | CRBNFKBP5OR51E2KDM4EGAA | |
| SCHEMBL279773 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL11629900 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62201973-A | — | — | None | — | — | JP | disclosed |
| JP-55147563-A | — | — | None | — | — | JP | disclosed |
| US-20210047324-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (HK) | 2021-02-18 | — | — | US | disclosed |
| WO-2019152678-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2019-08-08 | — | — | WO | disclosed |
| US-20130269890-A1 | TAMPON INCLUDING CROSSLINKED CELLULOSE FIBERS AND IMPROVED SYNTHESIS PROCESSES FOR PRODUCING SAME | EVEREADY BATTERY COMPANY, INC. | 2013-10-17 | — | — | US | disclosed |
| EP-1802697-B1 | ADDITIVE PACKAGE FOR THERMOPLASTIC CONDENSATION POLYMERS | DU PONT (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2264095-A1 | Additive package for thermoplastic condensation polymers | E. I. du Pont de Nemours and Company (US) | 2010-12-22 | — | — | EP | disclosed |
| EP-2240145-A2 | TAMPON INCLUDING CROSSLINKED CELLULOSE FIBERS AND IMPROVED SYNTHESIS PROCESSES FOR PRODUCING SAME | Playtex Products, Llc (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20090227975-A1 | TAMPON INCLUDING CROSSLINKED CELLULOSE FIBERS AND IMPROVED SYNTHESIS PROCESSES FOR PRODUCING SAME | PLAYTEX PRODUCTS, LLC (US) | 2009-09-10 | — | — | US | disclosed |
| WO-2009102913-A2 | TAMPON INCLUDING CROSSLINKED CELLULOSE FIBERS AND IMPROVED SYNTHESIS PROCESSES FOR PRODUCING SAME | PLAYTEX PRODUCTS, LLC (US) | 2009-08-20 | — | — | WO | disclosed |
| US-5843573-A | Polyester resin composition | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| US-5616681-A | CARRYING OUT RING-OPENING POLYMERIZATION OF CYCLIC ACID ANHYDRIDE WITH CYCLIC ETHER IN PRESENCE OF ZIRCONIUM COMPOUND | NIPPON SHOKUBAI CO., LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0718366-A2 | Polyester resin composition | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| EP-0710685-A2 | Process for producing aliphatic polyester | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |
| JP-S62201973-A | CURABLE RESIN COMPOSITION | TAKEDA CHEM IND LTD | 1987-09-05 | — | — | JP | disclosed |
| JP-S55147563-A | PAINT RESIN COMPOSITION | MITSUBISHI RAYON CO LTD | 1980-11-17 | — | — | JP | disclosed |
| US-4217436-A | N,N*-HYDROCARBYLENEDICARBONYLBIS/CYCLIC UREA/ | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4190599-A | ACRYLATE COPOLYMER AND EPOXY RESIN | THE UPJOHN COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4138398-A | Bis-cyclic ureas | THE UPJOHN COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
| US-3947428-A | BIS- OR TRIS-N,N-ETHYLENEUREA PROMOTER | MITSUBOSHI BELTING LTD. (JA) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047324-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN2B | CRBN 3123/4885FKBP5 362/4885OR51E2 388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.