Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.41 |
| ▸ | CCR8 | P51685 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16026600 | 0.85 | CCR1 (0.50) | CCR1CCR8LMNAHTTCCR5 | |
| SCHEMBL27977319 | 0.81 | LPL (0.39) | CCR1CCR8LMNAHTTCCR5 | |
| SCHEMBL14884183 | 0.76 | MAPT (0.42) | CCR1CCR8LMNAHTTCCR5 | |
| SCHEMBL14884167 | 0.76 | CCR1 (0.42) | CCR1CCR8LMNAHTTCCR5 | |
| SCHEMBL14884190 | 0.75 | CCR1 (0.41) | CCR1CCR8LMNAHTTCCR5 | |
| SCHEMBL27978517 | 0.71 | — | — | |
| SCHEMBL14884176 | 0.70 | CCR1 (0.37) | CCR1CCR8LMNAHTTCCR5 | |
| SCHEMBL14884189 | 0.70 | CCR1 (0.37) | CCR1CCR8LMNAHTTCCR5 | |
| SCHEMBL14884171 | 0.69 | ALDH1A1 (0.36) | CCR1CCR8LMNAHTTCCR5 | |
| SCHEMBL20003684 | 0.68 | LPL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039773-A | Cyclic azine compound having nitrogen-containing polycyclic aromatic group, method for producing same, and organic electroluminescent element comprising same as constituent component | TOSOH CORP | 2014-09-10 | — | — | CN | disclosed |