Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27977309 | 0.98 | EPHX1 (0.35) | SHBGEPHX1EPHX2NAAACHRM2 | |
| SCHEMBL27977583 | 0.94 | CHRM2 (0.38) | SHBGEPHX1CHRM2CHRM4CHRM1 | |
| SCHEMBL3784779 | 0.81 | SHBG (0.40) | SHBGEPHX1EPHX2NAAACHRM2 | |
| SCHEMBL15219463 | 0.81 | SHBG (0.40) | SHBGEPHX1EPHX2NAAACHRM2 | |
| SCHEMBL25022787 | 0.78 | EPHX1 (0.38) | SHBGEPHX1EPHX2NAAACHRM2 | |
| SCHEMBL10885190 | 0.78 | SHBG (0.38) | SHBGEPHX1EPHX2NAAACHRM2 | |
| SCHEMBL29094051 | 0.78 | SHBG (0.42) | SHBGEPHX1EPHX2NAAACHRM2 | |
| SCHEMBL28766886 | 0.77 | CHRM2 (0.36) | SHBGEPHX1EPHX2NAAACHRM2 | |
| SCHEMBL25021449 | 0.76 | EPHX1 (0.35) | SHBGEPHX1NAAACHRM2CHRM4 | |
| SCHEMBL24383740 | 0.74 | TP53 (0.40) | EPHX2ALDH1A1NPSR1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102007116-B | Pyridazinone glucokinase activators | HOFFMAN-LA ROCHE LTD. (CH) | 2014-10-22 | — | — | CN | disclosed |