Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190405 | 0.91 | DRD3 (0.55) | SLC6A4SLC6A3DRD3MEN1MAPT | |
| SCHEMBL8537416 | 0.85 | DRD3 (0.59) | SLC6A3DRD3MEN1MAPTKMT2A | |
| SCHEMBL9563370 | 0.85 | SLC6A2 (0.50) | SLC6A4SLC6A3DRD3CYP2D6DRD2 | |
| SCHEMBL4179768 | 0.84 | DRD3 (0.53) | SLC6A4SLC6A3DRD3MEN1MAPT | |
| SCHEMBL4179765 | 0.84 | DRD3 (0.53) | SLC6A4SLC6A3DRD3MEN1MAPT | |
| SCHEMBL4186866 | 0.84 | DRD3 (0.53) | SLC6A4SLC6A3DRD3MEN1MAPT | |
| SCHEMBL1499960 | 0.80 | SLC6A4 (0.49) | SLC6A4SLC6A3DRD3MEN1MAPT | |
| SCHEMBL2805296 | 0.80 | SLC6A4 (0.49) | SLC6A4SLC6A3DRD3MEN1MAPT | |
| SCHEMBL2803588 | 0.80 | SLC6A4 (0.49) | SLC6A4SLC6A3DRD3MEN1MAPT | |
| SCHEMBL17460152 | 0.79 | FAAH (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003978-A | Industrial preparation method for bepotastine besilate or racemoid of bepotastine besilate | JIANGSU LIANHUAN PHARMACEUTICAL CO LTD | 2014-08-27 | — | — | CN | disclosed |