Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | DRD1 | P21728 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802062 | 0.90 | DRD3 (0.59) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL2476701 | 0.89 | MAPK1 (0.60) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 | |
| SCHEMBL9533194 | 0.87 | FAAH (0.52) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 | |
| SCHEMBL27978433 | 0.85 | SLC6A4 (0.48) | SLC6A2SLC6A3DRD3CYP2D6SLC6A4 | |
| SCHEMBL12064698 | 0.83 | DRD3 (0.51) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 | |
| SCHEMBL12064699 | 0.83 | DRD3 (0.51) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 | |
| SCHEMBL12064952 | 0.83 | DRD3 (0.51) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 | |
| SCHEMBL9352969 | 0.81 | DRD3 (0.54) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 | |
| SCHEMBL14814326 | 0.81 | SLC6A2 (0.51) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 | |
| SCHEMBL8537416 | 0.81 | DRD3 (0.59) | SLC6A2SLC6A3CHRM2ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |