Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 2/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787203 | 0.87 | C3AR1 (0.36) | C3AR1FBP1HDAC1HDAC8HDAC6 | |
| SCHEMBL27784100 | 0.87 | C3AR1 (0.36) | C3AR1FBP1HDAC1HDAC8HDAC6 | |
| SCHEMBL27784102 | 0.87 | C3AR1 (0.36) | C3AR1FBP1HDAC1HDAC8HDAC6 | |
| SCHEMBL3583659 | 0.83 | C3AR1 (0.35) | C3AR1DAGLAFBP1CACNA1GSLC6A2 | |
| SCHEMBL15214452 | 0.77 | C3AR1 (0.40) | C3AR1DAGLA | |
| SCHEMBL1196600 | 0.75 | CACNA1G (0.38) | DAGLAFBP1CACNA1GSLC6A2SLC6A4 | |
| SCHEMBL800494 | 0.74 | KMT2A (0.48) | C3AR1 | |
| SCHEMBL3511397 | 0.74 | KMT2A (0.48) | C3AR1 | |
| SCHEMBL12980639 | 0.74 | C3AR1 (0.46) | C3AR1 | |
| SCHEMBL10045822 | 0.74 | C3AR1 (0.46) | C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104024258-A | Pyrrolopyrazine kinase inhibitors | HOFFMANN LA ROCHE | 2014-09-03 | — | — | CN | disclosed |