SCHEMBL27979160

SCHEMBL27979160

Cc1cc2ccc1-2.O=C(O)Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 6/20 0.47
AKR1C2 P52895 6/20 0.47
HSD17B1 P14061 1/20 0.47
ESR2 Q92731 2/20 0.47
ESR1 P03372 1/20 0.47
MCL1 Q07820 2/20 0.44
RARB P10826 1/20 0.41
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ADH5 P11766 2/20 0.39
SLC2A1 P11166 1/20 0.39
DGAT1 O75907 1/20 0.38
SOAT1 P35610 1/20 0.38
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
AKR1B10 O60218 1/20 0.37
AKR1C4 P17516 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11041891 0.88 HSD17B1 (0.53) AKR1C3AKR1C2HSD17B1ESR2ESR1
Bicarbonate SCHEMBL6362560 0.86 AKR1C3 (0.47) AKR1C3AKR1C2HSD17B1ESR2ESR1
SCHEMBL5334234 0.80
Bromide SCHEMBL28927015 0.80
Hydrogen Sulfide SCHEMBL28451021 0.80
Ammonia Solution, Strong SCHEMBL4602569 0.80
Formic Acid SCHEMBL28050270 0.79 ESR2 (0.48) AKR1C3AKR1C2HSD17B1ESR2ESR1
Boric Acid SCHEMBL28033106 0.78 ESR2 (0.52) AKR1C3AKR1C2HSD17B1ESR2ESR1
SCHEMBL2350935 0.78 ESR2 (0.52) AKR1C3AKR1C2HSD17B1ESR2ESR1
SCHEMBL31628308 0.77 ADH5 (0.56) HSD17B1RARBALDH1A1TSHRADH5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102131804-B Insecticidal compounds SYNGENTA PARTICIPATIONS AG 2014-12-03 CN disclosed