Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107238 | 0.81 | OPRM1 (0.41) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL783114 | 0.78 | FFAR3 (0.43) | SMN1; SMN2 | |
| Cyclohexane SCHEMBL6560747 | 0.76 | FFAR3 (0.42) | SMN1; SMN2POLB | |
| SCHEMBL1479275 | 0.76 | SMN1; SMN2 (0.38) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL5115722 | 0.74 | POLB (0.44) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL30707055 | 0.74 | OPRM1 (0.39) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL30142954 | 0.74 | SMN1; SMN2 (0.41) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL11800203 | 0.74 | FFAR3 (0.43) | SMN1; SMN2 | |
| SCHEMBL1742398 | 0.73 | SMN1; SMN2 (0.42) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL7369559 | 0.73 | SMN1; SMN2 (0.42) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980205-A | N-3-sulfonyl ethylamine substituted-5-cyclopropane spiro-hydantoin derivative as well as preparation method and application thereof | SYNCOM CHINA CO LTD WUHAN | 2014-08-13 | — | — | CN | disclosed |