Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107238 | 0.89 | OPRM1 (0.41) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL12764947 | 0.87 | POLB (0.40) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL11581057 | 0.85 | ALOX15 (0.48) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL4671349 | 0.84 | POLB (0.43) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL10950638 | 0.81 | POLB (0.44) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL1751418 | 0.79 | POLB (0.43) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL6736700 | 0.78 | POLB (0.46) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL30706658 | 0.77 | POLB (0.42) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL11218074 | 0.77 | POLB (0.42) | POLBALDH1A1OPRM1LMNAHSD17B10 | |
| SCHEMBL27692286 | 0.77 | POLB (0.42) | POLBALDH1A1OPRM1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015350-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2026-01-15 | — | — | US | disclosed |
| CN-119677749-A | Azaquinazoline pan KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20190248746-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | GUANGDONG MOLTECH PHARMA CO LTD (CN) | 2019-08-15 | — | — | US | disclosed |
| US-10315997-B2 | Cyclopropyl unsaturated quinoline compound used as leukotriene receptor antagonist and applications thereof | GUANGDONG MOLTECH PHARMA CO., LTD. (CN) | 2019-06-11 | — | — | US | disclosed |
| US-20180118687-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | GUANGDONG MOLTECH PHARMA CO., LTD. (CN) | 2018-05-03 | — | — | US | disclosed |
| US-7348344-B2 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2008-03-25 | — | — | US | disclosed |
| US-20070027191-A1 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248746-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | LTC4S, LTB4R, CYSLTR1 | POLB 3501/4885ALDH1A1 1624/4885OPRM1 972/4885 |
| US-20180118687-A1 | CYCLOPROPYL UNSATURATED QUINOLINE COMPOUND USED AS LEUKOTRIENE RECEPTOR ANTAGONIST AND APPLICATIONS THEREOF | LTC4S, LTB4R, CYSLTR1 | POLB 3551/4885ALDH1A1 1566/4885OPRM1 927/4885 |
| US-20070027191-A1 | Polysubstituted 1,1-pyridyloxycyclopropanamine compounds | CHRM1, CHRNA1, CHRNA9 | POLB 2363/4885ALDH1A1 680/4885OPRM1 39/4885 |
| US-20260015350-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | KRAS, NRAS, HRAS | POLB 1520/4885ALDH1A1 3667/4885OPRM1 2625/4885 |
| US-10315997-B2 | Cyclopropyl unsaturated quinoline compound used as leukotriene receptor antagonist and applications thereof | LTC4S, LTB4R, CYSLTR1 | POLB 3551/4885ALDH1A1 1566/4885OPRM1 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.