Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | LSS | P48449 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972988 | 0.86 | GSR (0.34) | EZH2ALDH1A1GSREZH1HRH3 | |
| SCHEMBL2587259 | 0.79 | CA12 (0.37) | EZH2CA12CA1CA2CA9 | |
| SCHEMBL2587361 | 0.79 | CA12 (0.35) | EZH2CA12CA1CA2CA9 | |
| SCHEMBL27973025 | 0.79 | CYP1A2 (0.38) | ALDH1A1MAPTGAAKDM4ETSHR | |
| SCHEMBL2592384 | 0.76 | LMNA (0.38) | EZH2CA12CA1CA2CA9 | |
| SCHEMBL19621034 | 0.73 | CA12 (0.32) | EZH2CA12CA1CA2CA9 | |
| SCHEMBL2592122 | 0.72 | CA12 (0.36) | EZH2CA12CA1CA2CA9 | |
| SCHEMBL14917583 | 0.71 | EZH2 (0.42) | EZH2CA12CA1CA2CA9 | |
| SCHEMBL2588982 | 0.70 | EZH2 (0.40) | EZH2CA12CA1CA2CA9 | |
| SCHEMBL2589118 | 0.70 | EZH2 (0.38) | EZH2ALDH1A1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039956-A | Method of treatment | GLAXOSMITHKLINE IP NO 2 LTD | 2014-09-10 | — | — | CN | disclosed |