Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979684 | 0.81 | GPR3 (0.50) | MEN1KMT2APTGER4MAPTPOLB | |
| SCHEMBL27979719 | 0.80 | ALDH1A1 (0.52) | MEN1KMT2ANPY5RPTGER4MAPT | |
| SCHEMBL13301258 | 0.79 | MEN1 (0.49) | MEN1KMT2ANPY5RPTGER4BCHE | |
| SCHEMBL27979731 | 0.78 | MEN1 (0.48) | MEN1KMT2ANPY5RPTGER4BCHE | |
| SCHEMBL2459822 | 0.77 | PTGER4 (0.59) | MEN1KMT2APTGER4MAPTTSHR | |
| SCHEMBL5096226 | 0.76 | NPY5R (0.47) | MEN1KMT2ANPY5RPTGER4BCHE | |
| SCHEMBL4728764 | 0.76 | MEN1 (0.56) | MEN1KMT2ANPY5RPTGER4BCHE | |
| SCHEMBL27979727 | 0.75 | MAPT (0.40) | MEN1KMT2ANPY5RPTGER4BCHE | |
| SCHEMBL27979879 | 0.74 | MEN1 (0.45) | MEN1KMT2ANPY5RPTGER4BCHE | |
| SCHEMBL29780042 | 0.74 | BCHE (0.59) | MEN1KMT2ANPY5RBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177377-A | 3-Position diamine beta-carboline alkali compound, and preparation method, medicinal composition and use thereof | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2014-12-03 | — | — | CN | disclosed |