SCHEMBL27979780

SCHEMBL27979780

O=[N+]([O-])C=Cc1ccc(Cl)cc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 5/20 0.50
MAPT P10636 4/20 0.45
ALDH1A1 P00352 4/20 0.45
NPSR1 Q6W5P4 3/20 0.45
HTT P42858 2/20 0.45
ALOX12 P18054 2/20 0.45
TLR4 O00206 5/20 0.43
TLR2 O60603 5/20 0.43
RXRA P19793 1/20 0.43
HSP90AA1 P07900 2/20 0.42
MEN1 O00255 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1722178 0.81 FBP1 (0.54) FBP1MAPTALDH1A1NPSR1HTT
SCHEMBL27673733 0.80 FBP1 (0.55) FBP1MAPTALDH1A1NPSR1HTT
SCHEMBL2077055 0.77 FBP1 (0.56) FBP1MAPTALDH1A1NPSR1HTT
SCHEMBL2077056 0.77 FBP1 (0.56) FBP1MAPTALDH1A1NPSR1HTT
SCHEMBL15175606 0.76 MAOA (0.58) FBP1TLR4TLR2MAOAMAOB
SCHEMBL15175604 0.76 MAOA (0.58) FBP1TLR4TLR2MAOAMAOB
SCHEMBL1983475 0.75 TDP1 (0.53) MAPTALDH1A1HTTMEN1CYP1A2
SCHEMBL5425639 0.75 PTGER3 (0.56) MAPTLMNANFKB1PTGDR2
SCHEMBL5425644 0.75 PTGER3 (0.56) MAPTLMNANFKB1PTGDR2
SCHEMBL1422411 0.74 FBP1 (0.53) FBP1MAPTALDH1A1NPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102348675-B Process for preparing substituted 2-nitrobiphenyls BASF SE (DE) 2014-10-01 CN disclosed