Chlorobenzene

Chlorobenzene

SCHEMBL27979893

Clc1ccccc1.O=C(Cc1ccccc1)c1ccccc1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.85
MAPT P10636 2/20 0.85
RAB9A P51151 5/20 0.59
NPC1 O15118 4/20 0.59
SRD5A2 P31213 2/20 0.59
SMO Q99835 1/20 0.53
MAPK1 P28482 2/20 0.52
TRPA1 O75762 1/20 0.52
ALDH1A1 P00352 1/20 0.52
GSK3B P49841 1/20 0.52
HIF1A Q16665 1/20 0.52
PLAU P00749 1/20 0.51
CES1 P23141 3/20 0.50
KMT2A Q03164 2/20 0.50
CES2 O00748 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
STS P08842 1/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL571046 0.92 L3MBTL1 (0.85) L3MBTL1MAPTRAB9ANPC1SRD5A2
SCHEMBL199869 0.92 L3MBTL1 (1.00) L3MBTL1MAPTRAB9ANPC1SRD5A2
Hydrochloric Acid SCHEMBL28260371 0.90 L3MBTL1 (0.82) L3MBTL1MAPTRAB9ANPC1SRD5A2
SCHEMBL24800 0.89 MAPT (0.73) L3MBTL1MAPTRAB9ANPC1SRD5A2
Parachlorophenol SCHEMBL28159625 0.89 L3MBTL1 (0.80) L3MBTL1MAPTRAB9ANPC1SRD5A2
Bicarbonate SCHEMBL28984888 0.87 MAPT (0.70) L3MBTL1MAPTRAB9ANPC1SRD5A2
Water SCHEMBL9243001 0.87 MAPT (0.70) L3MBTL1MAPTRAB9ANPC1SRD5A2
Water SCHEMBL20527670 0.87 MAPT (0.70) L3MBTL1MAPTRAB9ANPC1SRD5A2
SCHEMBL4282905 0.87 MAPT (0.70) L3MBTL1MAPTRAB9ANPC1SRD5A2
Hydrochloric Acid SCHEMBL27315608 0.87 MAPT (0.70) L3MBTL1MAPTRAB9ANPC1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104177392-B A kind of benzo B-N with fluorescent functional mixes pentalene and preparation method thereof NANKAI UNIVERSITY (CN) 2016-02-24 CN claimed
CN-104177392-A Benzo B-N heteropentalene with fluorescence function and preparation method thereof UNIV NANKAI 2014-12-03 CN claimed
CN-104177392-B A kind of benzo B-N with fluorescent functional mixes pentalene and preparation method thereof NANKAI UNIVERSITY (CN) 2016-02-24 CN disclosed
CN-104177392-A Benzo B-N heteropentalene with fluorescence function and preparation method thereof UNIV NANKAI 2014-12-03 CN disclosed