SCHEMBL571046

SCHEMBL571046

O=C(Cc1ccc(Cl)cc1)c1ccccc1

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.85
MAPT P10636 2/20 0.85
RAB9A P51151 5/20 0.70
NPC1 O15118 4/20 0.70
SMO Q99835 1/20 0.56
PLAU P00749 1/20 0.56
KMT2A Q03164 3/20 0.55
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 2/20 0.55
HPGD P15428 2/20 0.55
POLB P06746 1/20 0.55
CES2 O00748 1/20 0.55
CES1 P23141 1/20 0.55
SRD5A2 P31213 2/20 0.55
TDP1 Q9NUW8 1/20 0.54
MAPK1 P28482 2/20 0.52
TRPA1 O75762 1/20 0.52
GSK3B P49841 1/20 0.52
HIF1A Q16665 1/20 0.52
PIK3CA P42336 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28260371 0.98 L3MBTL1 (0.82) L3MBTL1MAPTRAB9ANPC1SMO
Chlorobenzene SCHEMBL27979893 0.92 L3MBTL1 (0.85) L3MBTL1MAPTRAB9ANPC1SMO
SCHEMBL199869 0.92 L3MBTL1 (1.00) L3MBTL1MAPTRAB9ANPC1ALDH1A1
SCHEMBL1753283 0.90 RAB9A (0.85) L3MBTL1MAPTRAB9ANPC1KMT2A
SCHEMBL7199268 0.89 MAPT (0.67) L3MBTL1MAPTRAB9ANPC1SMO
Parachlorophenol SCHEMBL28159625 0.89 L3MBTL1 (0.80) L3MBTL1MAPTRAB9ANPC1SMO
SCHEMBL6203266 0.87 L3MBTL1 (0.89) L3MBTL1MAPTRAB9ANPC1CES2
SCHEMBL1393818 0.86 L3MBTL1 (0.76) L3MBTL1MAPTRAB9ANPC1KMT2A
SCHEMBL24800 0.85 MAPT (0.73) L3MBTL1MAPTRAB9ANPC1PLAU
SCHEMBL28167868 0.85 L3MBTL1 (0.73) L3MBTL1MAPTRAB9ANPC1SMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269227-A Process for preparing 1,2, 3-trisubstituted indolizine derivatives 淮阴师范学院 2020-06-12 CN claimed
US-8815940-B2 Coumarin-chalcones as anticancer agents COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-08-26 US claimed
US-20130210909-A1 COUMARIN-CHALCONES AS ANTICANCER AGENTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-08-15 US claimed
EP-2601183-A1 COUMARIN-CHALCONES AS ANTICANCER AGENTS Council Of Scientific & Industrial Research (IN) 2013-06-12 EP claimed
WO-2012017454-A1 COUMARIN-CHALCONES AS ANTICANCER AGENTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-02-09 WO claimed
WO-2025040089-A1 NOVEL HETEROCYCLIC COMPOUND FOR SELECTIVELY REGULATING CANNABINOID CB1 FUNCTION 德睿智药(苏州)新药研发有限公司 2025-02-27 WO disclosed
US-20240368001-A1 SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-11-07 US disclosed
US-11987506-B2 Salt recovery solution and processes of use thereof AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2024-05-21 US disclosed
US-20230257284-A1 SALT RECOVERY SOLUTION AND PROCESSES OF USE THEREOF AQUAFORTUS TECHNOLOGIES LIMITED (NZ) 2023-08-17 US disclosed
US-20230234937-A1 INDENOAZANAPHTHALENES MERCK PATENT GMBH (DE) 2023-07-27 US disclosed
US-20230234937-A1 INDENOAZANAPHTHALENES MERCK PATENT GMBH (DE) 2023-07-27 US disclosed
US-20230234937-A1 INDENOAZANAPHTHALENES MERCK PATENT GMBH (DE) 2023-07-27 US disclosed
US-4898880-A N-(heterocycle)alkyl)-1H-pyrazole-1-alkanamides as antiarrhythmic agents, compositions and use STERLING DRUG INC. (US) 1990-02-06 US disclosed
US-4870095-A 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use STERLING DRUG, INC. (US) 1989-09-26 US disclosed
EP-0097822-B1 AMINOMETHYLDIOXOLANES AS PARASITICIDES BAYER AG (DE) 1987-07-15 EP disclosed
US-4668700-A AMINO KETALS, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed
US-4503059-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1985-03-05 US disclosed
EP-0097822-A1 Aminomethyldioxolanes as parasiticides BAYER AG (DE) 1984-01-11 EP disclosed
US-4344954-A DIURETICS AMERICAN CYANAMID COMPANY (US) 1982-08-17 US disclosed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234937-A1 INDENOAZANAPHTHALENES NQO1, CYP2D6, SQOR L3MBTL1 3664/4885MAPT 2276/4885RAB9A 3684/4885
US-20130210909-A1 COUMARIN-CHALCONES AS ANTICANCER AGENTS HCCS, XPO5, CIAPIN1 L3MBTL1 4296/4885MAPT 3772/4885RAB9A 3704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.