Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107937 | 0.84 | TLR9 (0.39) | TLR9GAACA1CA2MEN1 | |
| SCHEMBL27592268 | 0.82 | TLR9 (0.38) | TLR9GAACA1CA2MEN1 | |
| SCHEMBL27275837 | 0.82 | MAPK1 (0.37) | CA1CA2MEN1KMT2ACA12 | |
| SCHEMBL28795710 | 0.81 | TGM2 (0.40) | MEN1KMT2ATGM2CYP3A4 | |
| SCHEMBL28793737 | 0.81 | IDO1 (0.32) | GAACA1CA2TGM2MMP1 | |
| SCHEMBL27844721 | 0.80 | GRIA4 (0.41) | GAACA1CA2MEN1KMT2A | |
| SCHEMBL1173054 | 0.80 | HSD17B10 (0.38) | MEN1KMT2AALDH1A1TDP1CYP3A4 | |
| SCHEMBL27844867 | 0.78 | CYP3A4 (0.40) | CA1CA2MEN1KMT2ACA12 | |
| SCHEMBL27857728 | 0.77 | HSD11B1 (0.38) | CA1CA2CA9TGM2 | |
| SCHEMBL27918899 | 0.77 | GRIA4 (0.36) | TLR9GAACA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736530-A | Compounds for the treatment of paramoxyvirus viral infections | ALIOS BIOPHARMA INC | 2015-06-24 | — | — | CN | disclosed |
| CN-103987707-A | Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use | HOFFMANN LA ROCHE | 2014-08-13 | — | — | CN | disclosed |